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Nuclear Functions of Actin
Stockholm University, Faculty of Science, Department of Molecular Biology and Functional Genomics.
2010 (English)In: COLD SPRING HARBOR PERSPECT B, ISSN 1943-0264, Vol. 2, no 4, a000620- p.Article in journal (Refereed) Published
Abstract [en]

Actin participates in several essential processes in the cell nucleus. Even though the presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes that require actin have been only recently identified. Actin is part of chromatin remodeling complexes; it is associated with the transcription machineries; it becomes incorporated into newly synthesized ribonucleoproteins; and it influences long-range chromatin organization. As in the cytoplasm, nuclear actin works in conjunction with different types of actin-binding proteins that regulate actin function and bridge interactions between actin and other nuclear components.

Place, publisher, year, edition, pages
2010. Vol. 2, no 4, a000620- p.
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:su:diva-49202DOI: 10.1101/cshperspect.a000620ISI: 000279882300005OAI: diva2:377054
authorCount :2Available from: 2010-12-13 Created: 2010-12-13 Last updated: 2010-12-13Bibliographically approved

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