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Sensitivity and specificity of the nickel spot (dimethylglyoxime) test
Stockholm University, Faculty of Science, Department of Applied Environmental Science (ITM).
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2010 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 62, no 5, 279-288 p.Article in journal (Refereed) Published
Abstract [en]

Objectives: To evaluate the sensitivity and specificity of the DMG test. Methods: DMG spot testing, chemical analysis according to the EN 1811 reference method, and X-ray fluorescence spectroscopy (XRF) were performed concomitantly on 96 metallic components from earrings recently purchased in San Francisco. Results: The sensitivity of the DMG test was 59.3% and the specificity was 97.5% based on DMG-test results and nickel release concentrations determined by the EN 1811 reference method. Conclusions: The DMG test has a high specificity but a modest sensitivity. It may serve well for screening purposes. Past exposure studies may have underestimated nickel release from consumer items.

Place, publisher, year, edition, pages
2010. Vol. 62, no 5, 279-288 p.
Keyword [en]
chemical analyses, dimethylglyoxime test, nickel release, sensitivity, specificity, validation
National Category
Natural Sciences
URN: urn:nbn:se:su:diva-50499ISI: 000277000100003OAI: diva2:383552
authorCount :7Available from: 2011-01-05 Created: 2010-12-28 Last updated: 2011-01-05Bibliographically approved

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Lundgren, Lennart
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