Sensitivity and specificity of the nickel spot (dimethylglyoxime) test
2010 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 62, no 5, 279-288 p.Article in journal (Refereed) Published
Objectives: To evaluate the sensitivity and specificity of the DMG test. Methods: DMG spot testing, chemical analysis according to the EN 1811 reference method, and X-ray fluorescence spectroscopy (XRF) were performed concomitantly on 96 metallic components from earrings recently purchased in San Francisco. Results: The sensitivity of the DMG test was 59.3% and the specificity was 97.5% based on DMG-test results and nickel release concentrations determined by the EN 1811 reference method. Conclusions: The DMG test has a high specificity but a modest sensitivity. It may serve well for screening purposes. Past exposure studies may have underestimated nickel release from consumer items.
Place, publisher, year, edition, pages
2010. Vol. 62, no 5, 279-288 p.
chemical analyses, dimethylglyoxime test, nickel release, sensitivity, specificity, validation
IdentifiersURN: urn:nbn:se:su:diva-50499ISI: 000277000100003OAI: oai:DiVA.org:su-50499DiVA: diva2:383552
authorCount :72011-01-052010-12-282011-01-05Bibliographically approved