Change search
ReferencesLink to record
Permanent link

Direct link
A graphic user interface toolkit for specification, report and comparison of dose-response relations and treatment plans using the biologically effective uniform dose
Stockholm University, Faculty of Science, Medical Radiation Physics (together with KI).
Show others and affiliations
2010 (English)In: Computer Methods and Programs in Biomedicine, ISSN 0169-2607, E-ISSN 1872-7565, Vol. 100, no 1, 69-78 p.Article in journal (Refereed) Published
Abstract [en]

A toolkit (BEUDcal) has been developed for evaluating the effectiveness and for predicting the outcome of treatment plans by calculating the biologically effective uniform dose (BEUD) and complication-free tumor control probability. The input for the BEUDcal is the differential dose-volume histograms of organs exported from the treatment planning system. A clinical database is built for the dose-response parameters of different tumors and normal tissues. Dose-response probabilities of all the examined organs are illustrated together with the corresponding BEUDs and the P+ values. Furthermore, BEUDcal is able to generate a report that simultaneously presents the radiobiological evaluation together with the physical dose indices, showing the complementary relation between the physical and radiobiological treatment plan analysis performed by BEUDcal. Comparisons between treatment plans for helical tomotherapy and multileaf collimator-based intensity modulated radiotherapy of a lung patient were demonstrated to show the versatility of BEUDcal in the assessment and report of dose-response relations.

Place, publisher, year, edition, pages
2010. Vol. 100, no 1, 69-78 p.
Keyword [en]
Biologically effective uniform dose, Helical tomotherapy, Treatment planning, Radiobiological objectives
National Category
Natural Sciences
URN: urn:nbn:se:su:diva-51752DOI: 10.1016/j.cmpb.2010.02.003ISI: 000282391500007OAI: diva2:386033
authorCount :5Available from: 2011-01-12 Created: 2011-01-12 Last updated: 2011-01-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Medical Radiation Physics (together with KI)
In the same journal
Computer Methods and Programs in Biomedicine
Natural Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 13 hits
ReferencesLink to record
Permanent link

Direct link