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Mutagenesis: mutating a gene while reading it.
Stockholm University, Faculty of Science, Department of Genetics, Microbiology and Toxicology.
2010 (English)In: Current Biology, ISSN 0960-9822, E-ISSN 1879-0445, Vol. 20, no 2, R57-8 p.Article, review/survey (Refereed) Published
Abstract [en]

Is it possible to mutate DNA during transcription? A new study shows that UV-damaged DNA is deaminated during transcription, which is a probable mechanism underlying CC tandem mutations found in the p53 gene in skin cancers.

Place, publisher, year, edition, pages
2010. Vol. 20, no 2, R57-8 p.
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URN: urn:nbn:se:su:diva-52957DOI: 10.1016/j.cub.2009.11.047PubMedID: 20129038OAI: oai:DiVA.org:su-52957DiVA: diva2:389463
Available from: 2011-01-19 Created: 2011-01-19 Last updated: 2017-12-11Bibliographically approved

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