A transmembrane inner nuclear membrane protein in the mitotic spindle
2010 (English)In: Nucleus (Austin), ISSN 1949-1042, Vol. 1, no 3, 249-253 p.Article in journal (Refereed) Published
We have recently characterized a novel transmembrane protein of the inner nuclear membrane of mammalian cells. The protein has two very interesting features. First, despite being an integral membrane protein it is able to concentrate in the membranes colocalizing with the mitotic spindle in metaphase and anaphase. Hence, the protein was named Samp1, Spindle associated membrane protein 1. Secondly, it displays a functional connection to centrosomes. This article discusses various aspects of Samp1 in relation to possible cellular function(s).
Place, publisher, year, edition, pages
2010. Vol. 1, no 3, 249-253 p.
inner nuclear membrane, transmembrane proteins, mitotic spindle, spindle matrix, mitosis, cancer, LINC complex, centrosome, dystonia
Biological Sciences Chemical Sciences
Research subject Neurochemistry with Molecular Neurobiology
IdentifiersURN: urn:nbn:se:su:diva-53568OAI: oai:DiVA.org:su-53568DiVA: diva2:391127