Change search
ReferencesLink to record
Permanent link

Direct link
Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report.
Show others and affiliations
2011 (English)In: Occupational and Environmental Medicine, ISSN 1351-0711, E-ISSN 1470-7926, Vol. 68, no 2, 154-162 p.Article in journal (Refereed) Published
Abstract [en]

Based on the idea that electric light at night might account for a portion of the high and rising risk of breast cancer worldwide, it was predicted long ago that women working a non-day shift would be at higher risk compared with day-working women. This hypothesis has been extended more recently to prostate cancer. On the basis of limited human evidence and sufficient evidence in experimental animals, in 2007 the International Agency for Research on Cancer (IARC) classified 'shift work that involves circadian disruption' as a probable human carcinogen, group 2A. A limitation of the epidemiological studies carried out to date is in the definition of 'shift work.' IARC convened a workshop in April 2009 to consider how 'shift work' should be assessed and what domains of occupational history need to be quantified for more valid studies of shift work and cancer in the future. The working group identified several major domains of non-day shifts and shift schedules that should be captured in future studies: (1) shift system (start time of shift, number of hours per day, rotating or permanent, speed and direction of a rotating system, regular or irregular); (2) years on a particular non-day shift schedule (and cumulative exposure to the shift system over the subject's working life); and (3) shift intensity (time off between successive work days on the shift schedule). The group also recognised that for further domains to be identified, more research needs to be conducted on the impact of various shift schedules and routines on physiological and circadian rhythms of workers in real-world environments.

Place, publisher, year, edition, pages
2011. Vol. 68, no 2, 154-162 p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:su:diva-53713DOI: 10.1136/oem.2009.053512ISI: 000286223300014PubMedID: 20962033Local ID: P2845OAI: diva2:391208
Available from: 2011-01-24 Created: 2011-01-24 Last updated: 2012-01-20Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Lowden, Arne
By organisation
Stress Research Institute
In the same journal
Occupational and Environmental Medicine
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 59 hits
ReferencesLink to record
Permanent link

Direct link