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Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans
Stockholm University, Faculty of Science, Department of Neurochemistry.
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2007 (English)In: Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, E-ISSN 1098-6596, Vol. 51, no 11, 4167-4170 p.Article in journal (Refereed) Published
Abstract [en]

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

Place, publisher, year, edition, pages
2007. Vol. 51, no 11, 4167-4170 p.
Keyword [en]
human keratinocytes, nervous-system, resistance, expression, receptors, skin
National Category
Chemical Sciences
URN: urn:nbn:se:su:diva-55754DOI: 10.1128/AAC.00166-07ISI: 000250612900053OAI: diva2:406922
authorCount :5Available from: 2011-03-29 Created: 2011-03-28 Last updated: 2011-03-29Bibliographically approved

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