Palladium-catalyzed C-H functionalization of alkenes under oxidative conditions
2011 (English)Licentiate thesis, comprehensive summary (Other academic)
The unique properties of high oxidation state palladium have been used to develop new catalytic alkene C-H functionalization reactions. A Heck-type coupling based on the reactivity of palladium catalysts and diaryliodonium salts has been developed with broad synthetic scope and tolerance for functional groups that are ordinarily reactive in Pd0/PdII catalysis, for example, allylic acetates and aryl bromides. Poisoning experiments and DFT studies suggest that a PdII/PdIV cycle is operating. The first catalytic allylic C-H silylation method has also been developed utilizing commercially available hexamethyldisilane as silyl source and iodine(III) reagents as oxidants.
Place, publisher, year, edition, pages
Stockholm: Stockholms universitet , 2011. , 27 p.
IdentifiersURN: urn:nbn:se:su:diva-57764OAI: oai:DiVA.org:su-57764DiVA: diva2:417911
2011-05-02, Magnéli Hall, Kemiska övningslaboratoriet, Svante Arrhenius väg 16 B, Stockholm, 14:00 (English)
Borbas, Eszter, Doktor
Szabó, Kálmán, Professor