Glycan structure of a high-mannose glycoprotein from Raman optical activity
2011 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 50, no 23, 5349-5351 p.Article in journal (Refereed) Published
A revealing signature: The glycan structure of intact yeast external invertase, a high-mannose glycoprotein used as biocatalyst, was investigated by using Raman optical activity (ROA) spectroscopy. The conformational preferences present in mannose-containing di- and trisaccharides were found to be preserved in the glycan chains, with secondary polpeptide backbone structure suppressed.
Place, publisher, year, edition, pages
2011. Vol. 50, no 23, 5349-5351 p.
glycoproteins, glycosylation, invertase, Raman optical activity
IdentifiersURN: urn:nbn:se:su:diva-57979DOI: 10.1002/anie.201008258ISI: 000291953200021OAI: oai:DiVA.org:su-57979DiVA: diva2:419120
FunderSwedish Research CouncilKnut and Alice Wallenberg Foundation