Change search
ReferencesLink to record
Permanent link

Direct link
Multiscale modeling of biological functions
Stockholm University, Faculty of Science, Department of Organic Chemistry.
2011 (English)In: Physical Chemistry, Chemical Physics - PCCP, ISSN 1463-9076, E-ISSN 1463-9084, Vol. 13, no 22, 10401-10411 p.Article in journal (Refereed) Published
Abstract [en]

Recent years have witnessed a tremendous explosion in computational power, which in turn has resulted in great progress in the complexity of the biological and chemical problems that can be addressed by means of all-atom simulations. Despite this, however, our computational time is not infinite, and in fact many of the key problems of the field were resolved long before the existence of the current levels of computational power. This review will start by presenting a brief historical overview of the use of multiscale simulations in biology, and then present some key developments in the field, highlighting several cases where the use of a physically sound simplification is clearly superior to a brute-force approach. Finally, some potential future directions will be discussed.

Place, publisher, year, edition, pages
2011. Vol. 13, no 22, 10401-10411 p.
National Category
Physical Chemistry
Research subject
URN: urn:nbn:se:su:diva-58038DOI: 10.1039/C0CP02823AISI: 000290994900002OAI: diva2:419784
Swedish Research Council, 2010-5026
Available from: 2011-05-28 Created: 2011-05-28 Last updated: 2012-01-20Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Kamerlin, Shina C. L.
By organisation
Department of Organic Chemistry
In the same journal
Physical Chemistry, Chemical Physics - PCCP
Physical Chemistry

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 26 hits
ReferencesLink to record
Permanent link

Direct link