Dynamic Kinetic Resolution of β-Amino Esters by a Heterogeneous System of a Palladium Nanocatalyst and Candida antarctica Lipase A
2011 (English)In: European Journal of Organic Chemistry, ISSN 1434-193X, E-ISSN 1099-0690, no 10, 1827-1830 p.Article in journal (Refereed) Published
A dynamic kinetic resolution (DKR) of β-amino esters have been developed by the use of a heterogeneous racemization catalyst and an immobilized enzyme that accepts aromatic, heteroaromatic and aliphatic substrates. The reaction conditions were optimized to yield an efficient catalytic system without by-product formation. The products are obtained in 96–99 % ee and high yields
Place, publisher, year, edition, pages
2011. no 10, 1827-1830 p.
dynamic kinetic resolution, β-Amino esters, candida antarctica lipase A, palladium, nanocatalysts, heterogeneous catalysis
IdentifiersURN: urn:nbn:se:su:diva-59868DOI: 10.1002/ejoc.201001714ISI: 000288611700002OAI: oai:DiVA.org:su-59868DiVA: diva2:431544
FunderEU, FP7, Seventh Framework ProgrammeKnut and Alice Wallenberg Foundation