CO dissociation mechanism in racemization of alcohols by a cyclopentadienyl ruthenium dicarbonyl catalyst
2011 (English)In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 133, no 9, 2820-2823 p.Article in journal (Refereed) Published
13CO exchange studies of racemization catalyst (η5-Ph5C5)Ru(CO)2Cl and (η5-Ph5C5)Ru(CO)2(Ot-Bu) by 13C NMR spectroscopy are reported. CO exchange for the active catalyst form, (η5-Ph5C5)Ru(CO)2(Ot-Bu) is approximately 20 times faster than that for the precatalyst (η5-Ph5C5)Ru(CO)2Cl. An inhibition on the rate of racemization of (S)-1-phenylethanol was observed on addition of CO. These results support the hypothesis that CO dissociation is a key step in the racemization of sec-alcohols by (η5-Ph5C5)Ru(CO)2Cl, as also predicted by DFT calculations.
Place, publisher, year, edition, pages
2011. Vol. 133, no 9, 2820-2823 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-59869DOI: 10.1021/ja1098066ISI: 000289455200008OAI: oai:DiVA.org:su-59869DiVA: diva2:431551
FunderSwedish Research CouncilKnut and Alice Wallenberg Foundation