Metal-free synthesis of aryl esters from carboxylic acids and diaryliodonium salts
2011 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 13, no 13, 3462-3465 p.Article in journal (Refereed) Published
An efficient arylation of carboxylic acids with diaryliodonium salts has been developed, giving aryl esters in high yields within short reaction times for both arom. and aliph. substrates. The transition-metal-free conditions are compatible with a range of functional groups, and good chemoselectivity is obsd. with unsym. diaryliodonium salts. Furthermore, steric hindrance in the ortho positions is well tolerated both in the carboxylic acid and in the diaryliodonium salt, yielding aryl esters that cannot be obtained via other esterification protocols.
Place, publisher, year, edition, pages
2011. Vol. 13, no 13, 3462-3465 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-59894DOI: 10.1021/ol2012082ISI: 000291920800045OAI: oai:DiVA.org:su-59894DiVA: diva2:431829
FunderCarl Tryggers foundation , 08:288Carl Tryggers foundation , 09:281Swedish Research Council, 621-2008-3709