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Europium-based turn-on bioconjugatable luminescent probe for detecting H2O2 in live cells.
Stockholm University, Faculty of Science, Department of Organic Chemistry.
2011 (English)In: Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011, 2011Conference paper, Published paper (Other academic)
Abstract [en]

A Europium-based turn-on bioconjugatable luminescent probe for detecting hydrogen peroxide in live cells is presented.  The probe relies on a chemoselective boronate-to-phenol switch in response to hydrogen peroxide, resulting in an enhanced lanthanide sensitization.  Excitation can be performed by visible light.  Bioconjugation is achived by Cu(I) catalyzed azide-alkyne cycloaddn.

Place, publisher, year, edition, pages
2011.
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:su:diva-64323OAI: oai:DiVA.org:su-64323DiVA: diva2:457025
Conference
242nd ACS National Meeting & Exposition, Denver, CO, United States
Available from: 2011-11-16 Created: 2011-11-16 Last updated: 2011-11-17Bibliographically approved

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