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Preparation of glycosylated pyrroles, and their use in the synthesis of analogs of the multi drug resistance-reversing natural product Tolyporphin
Stockholm University, Faculty of Science, Department of Organic Chemistry.
2011 (English)In: Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011, 2011Conference paper, Published paper (Other academic)
Abstract [en]

We present methods for the highly regio- and stereoselective synthesis of glycosylated pyrroles, and the incorporation of these compds. into larger oligopyrrolic architectures (dipyrromethanes, porphyrins, chlorins).  The flexibility of the synthesis enables the rapid generation of a wide  variety of structures.  The products are expected to be useful as synthetically accessible analogs of the biol. active natural product Tolyporphin, as well as imaging tools for biomedical applications.

Place, publisher, year, edition, pages
2011.
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:su:diva-64427OAI: oai:DiVA.org:su-64427DiVA: diva2:457302
Conference
242nd ACS National Meeting & Exposition, Denver, CO, United States
Available from: 2011-11-17 Created: 2011-11-17Bibliographically approved

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CiteExportLink to record
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