Preparation of glycosylated pyrroles, and their use in the synthesis of analogs of the multi drug resistance-reversing natural product Tolyporphin
2011 (English)In: Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011, 2011Conference paper (Other academic)
We present methods for the highly regio- and stereoselective synthesis of glycosylated pyrroles, and the incorporation of these compds. into larger oligopyrrolic architectures (dipyrromethanes, porphyrins, chlorins). The flexibility of the synthesis enables the rapid generation of a wide variety of structures. The products are expected to be useful as synthetically accessible analogs of the biol. active natural product Tolyporphin, as well as imaging tools for biomedical applications.
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IdentifiersURN: urn:nbn:se:su:diva-64427OAI: oai:DiVA.org:su-64427DiVA: diva2:457302
242nd ACS National Meeting & Exposition, Denver, CO, United States