Nanodosimetry in a (12)C ion beam using Monte Carlo simulations
2010 (English)In: Radiation Measurements, ISSN 1350-4487, Vol. 45, no 10, 1238-1241 p.Article in journal (Refereed) Published
The dose-mean lineal energy, (y) over bar (D), has been calculated in water for irradiation with (12)C ions with initial energies 290 MeV/u. The y, was evaluated from the energy distributions of carbon and secondary boron ions, and from their energy-dependent pp-values. The energy distributions were obtained from simulations with the Monte Carlo code SHIELD-HIT07 and the energy-dependent (y) over bar (D)-values were obtained from ion-track simulations with PITS99 coupled with the electron transport code KURBUC. The ratio of the (y) over bar (D)-value determined in the vicinity of the Bragg peak to that calculated in a reference (60)Co gamma beam was compared with the corresponding ratio of alpha-values from the linear-quadratic model used in fractionated radiotherapy, showing a good correlation for an object size of around 10 nm.
Place, publisher, year, edition, pages
2010. Vol. 45, no 10, 1238-1241 p.
Microdosimetry, Nanodosimetry, Carbon ion radiotherapy, Monte Carlo simulation
IdentifiersURN: urn:nbn:se:su:diva-66241DOI: 10.1016/j.radmeas.2010.05.033ISI: 000286349000038OAI: oai:DiVA.org:su-66241DiVA: diva2:467416
authorCount :52011-12-192011-12-192011-12-19Bibliographically approved