Palladium-Catalyzed Allylic C-OH Functionalization for Efficient Synthesis of Functionalized Allylsilanes
2011 (English)In: Journal of the American Chemical Society, ISSN 0002-7863, E-ISSN 1520-5126, Vol. 133, no 3, 409-411 p.Article in journal (Refereed) Published
A new method is described for palladium-catalyzed allylic silylation using allylic alcohols and disilanes as precursors. The reactions proceed smoothly under mild and neutral conditions, and this method is suitable for synthesis of regio-and stereodefined allylsilanes. The presented silylation reaction can be easily extended to include synthesis of allylboronates by change of the dimetallic reagent. The presented synthetic procedure offers a broad platform for the selective synthesis of functionalized allyl metal reagents, which are useful precursors in advanced organic chemistry and natural product synthesis.
Place, publisher, year, edition, pages
2011. Vol. 133, no 3, 409-411 p.
IdentifiersURN: urn:nbn:se:su:diva-67339DOI: 10.1021/ja1096732ISI: 000287553000007OAI: oai:DiVA.org:su-67339DiVA: diva2:470288
authorCount :32011-12-282011-12-282011-12-28Bibliographically approved