Change search
ReferencesLink to record
Permanent link

Direct link
Gender role behaviour in prenatally dexamethasone-treated children at risk for congenital adrenal hyperplasia - a pilot study
Stockholm University, Faculty of Social Sciences, Department of Psychology.
2011 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 100, no 9, e112-E119 p.Article in journal (Refereed) Published
Abstract [en]

Aim: To investigate the effects of prenatal dexamethasone (DEX) exposure on gender role behaviour. Methods: The participants were 25 of the 40 children (62%, mean age 11 years) at risk for CAH treated with DEX prenatally during the years 1985-1995 in Sweden. The control group consisted of 35 sex- and age-matched healthy children. A new inventory, the Karolinska Inventory of Gender Role Behaviour (KI-GRB), was developed to assess directly school-age children's behaviour, and was evaluated using a separate sample of 160 school-age children. Results: DEX-treated CAH-unaffected boys showed more neutral behaviours than the controls (p = 0.04), while the DEX-treated CAH-unaffected girls did not differ from the controls after adjusting for the site of residence. There was a larger variation in the behaviour of the DEX-treated boys (p < 0.05) and a tendency for less-masculine behaviours in the DEX-treated CAH-unaffected children (p = 0.13). There were no between-group differences in the feminine behaviours. Recalculation of the analyses including the CAH-affected children showed analogous results. Conclusions: This pilot study indicates that the gender role behaviour may be affected in boys as an effect of DEX exposure in early pregnancy. Larger retrospective studies are needed for more conclusive results.

Place, publisher, year, edition, pages
2011. Vol. 100, no 9, e112-E119 p.
Keyword [en]
congenital adrenal hyperplasia, dexamethasone, gender role behaviour, prenatal treatment, sex-typed behaviour
National Category
Social Sciences Medical and Health Sciences
Research subject
URN: urn:nbn:se:su:diva-68025DOI: 10.1111/j.1651-2227.2011.02260.xISI: 000293942500004OAI: diva2:471855
authorCount :4Available from: 2012-01-03 Created: 2012-01-02 Last updated: 2012-02-03Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Lindholm, Torun
By organisation
Department of Psychology
In the same journal
Acta Paediatrica
Social SciencesMedical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 16 hits
ReferencesLink to record
Permanent link

Direct link