Recent developments in trace analysis of poly- and perfluoroalkyl substances
2011 (English)In: Analytical and Bioanalytical Chemistry, ISSN 1618-2642, E-ISSN 1618-2650, Vol. 400, no 6, 1625-1635 p.Article in journal (Refereed) Published
Recent developments, improvements, and trends in the ultra-trace determination of per- and polyfluoroalkyl substances (PFASs) in environmental and human samples are highlighted and the remaining challenges and uncertainties are outlined and discussed. Understanding the analytical implications of such things as adsorption of PFASs to surfaces, effects of differing matrices, varying PFAS isomer response factors, potential bias effects of sampling, sample preparation, and analysis is critical to measuring highly fluorinated compounds at trace levels. These intricate analytical issues and the potential consequences of ignoring to deal with them correctly are discussed and documented with examples. Isomer-specific analysis and the development of robust multi-chemical methods are identified as topical trends in method development for an ever-increasing number of PFASs of environmental and human interest. Ultimately, the state-of-the-art of current analytical method accuracy is discussed on the basis of results from interlaboratory comparison studies.
Place, publisher, year, edition, pages
2011. Vol. 400, no 6, 1625-1635 p.
Perfluoro, Highly fluorinated, PFASs, Analysis, Environmental, Human
Earth and Related Environmental Sciences
IdentifiersURN: urn:nbn:se:su:diva-68121DOI: 10.1007/s00216-011-4823-8ISI: 000290570200015OAI: oai:DiVA.org:su-68121DiVA: diva2:472261
authorCount :52012-01-032012-01-032012-01-03Bibliographically approved