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Trends in the bioanalytical applications of microfluidic electrocapture
Stockholm University, Faculty of Science, Department of Analytical Chemistry.
Stockholm University, Faculty of Science, Department of Analytical Chemistry.
2011 (English)In: Analytical and Bioanalytical Chemistry, ISSN 1618-2642, E-ISSN 1618-2650, Vol. 399, no 1, 191-195 p.Article in journal (Refereed) Published
Abstract [en]

Downscaled analytical tools for sample preparation have offered benefits such as higher throughput, easier automation and lower sample/reagent consumption. Microfluidic electrocapture, which is a newly developed sample preparation/manipulation system, uses an electric field to trap and separate charged species without using any solid sorbent. The feasibility of using microfluidic electrocapture is reported for separation, clean-up, concentration, microreactions and complexation studies of proteins, peptides and other biologically important biomolecules. The instrumentation and applications of microfluidic electrocapture are reviewed and an overview is provided of future perspectives offered by the current and envisaged platforms.

Place, publisher, year, edition, pages
2011. Vol. 399, no 1, 191-195 p.
Keyword [en]
Sample preparation, Mass spectrometry, Microfluidic, Electrocapture
National Category
Biochemistry and Molecular Biology Analytical Chemistry
Identifiers
URN: urn:nbn:se:su:diva-68375DOI: 10.1007/s00216-010-4092-yISI: 000285781200019OAI: oai:DiVA.org:su-68375DiVA: diva2:472849
Note
authorCount :3Available from: 2012-01-04 Created: 2012-01-03 Last updated: 2017-12-08Bibliographically approved

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