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Classes and prediction of cell-penetrating peptides
Stockholm University, Faculty of Science, Department of Neurochemistry.
Stockholm University, Faculty of Science, Department of Neurochemistry. Tartu University, Estonia.ORCID iD: 0000-0001-6107-0844
2011 (English)In: Cell-penetrating peptides: Methods and Protocols / [ed] Ülo Langel, New York: Humana Press, 2011, 3-19 p.Chapter in book (Other academic)
Abstract [en]

The classical view on how peptides enter cells has been changed due to the development in the research field of cell-penetrating peptides (CPPs). During the last 15 years, more than 100 peptide sequences have been published to enter cells and also to bring different biological cargoes with them. Here, we present an overview of CPPs, mainly trying to analyze their common properties yielding the prediction of their cell-penetrating properties. Furthermore, examples of recent research, ideas on classification and uptake mechanisms, as well as a summary of the therapeutic potential of CPPs are presented.

Place, publisher, year, edition, pages
New York: Humana Press, 2011. 3-19 p.
, Methods in Molecular Biology, ISSN 1064-3745 ; 683
Keyword [en]
cpp, cell-penetrating peptides, transfection, Cell-penetrating peptide, Cellular uptake, Intracellular delivery, Drug delivery, siRNA, Selective delivery
National Category
Chemical Sciences Biological Sciences
Research subject
Neurochemistry with Molecular Neurobiology
URN: urn:nbn:se:su:diva-70599DOI: 10.1007/978-1-60761-919-2_1ISBN: 978-1-60761-918-5OAI: diva2:482102
Available from: 2012-01-23 Created: 2012-01-23 Last updated: 2015-04-21Bibliographically approved

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