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THE EXPRESSION OF MUSCLE ANKYRIN REPEAT PROTEINS IN BROWN ADIPOSE TISSUE
Stockholm University, Faculty of Science, The Wenner-Gren Institute , Physiology.
2011 (English)In: ARCHIVES OF BIOLOGICAL SCIENCES, ISSN 0354-4664, Vol. 63, no 4, 915-920 p.Article in journal (Refereed) Published
Abstract [en]

MARP family members CARP, Ankrd2 and DARP are expressed in the striated muscle, while DARP protein is also detected in brown adipose tissue (BAT). Taking into account recent findings concerning the common origin of muscle and brown fat, expression of CARP and Ankrd2 in mouse BAT was investigated. We demonstrated Ankrd2 expression in both inactive and thermogenically active BAT, while CARP expression was not detected. Our findings suggest that the expression of Ankrd2 in BAT could be a part of the myogenic transcriptional signature, further supporting the evidence that muscle and brown adipose cells arise from the same myoblastic precursor.

Place, publisher, year, edition, pages
2011. Vol. 63, no 4, 915-920 p.
Keyword [en]
MARP family, brown adipose tissue
National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:su:diva-74050DOI: 10.2298/ABS1104915RISI: 000299244500001OAI: oai:DiVA.org:su-74050DiVA: diva2:506670
Note
authorCount :4Available from: 2012-02-29 Created: 2012-02-28 Last updated: 2012-02-29Bibliographically approved

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