Change search
ReferencesLink to record
Permanent link

Direct link
The dynamics of change in striatal activity following updating training
Show others and affiliations
2013 (English)In: Human Brain Mapping, ISSN 1065-9471, E-ISSN 1097-0193, Vol. 34, no 7, 1530-1541 p.Article in journal (Refereed) Published
Abstract [en]

Increases in striatal activity have been suggested to mediate training-related improvements in working-memory ability. We investigated the temporal dynamics of changes in task-related brain activity following training of working memory. Participants in an experimental group and an active control group, trained on easier tasks of a constant difficulty in shorter sessions than the experimental group, were measured before, after about 1 week, and after more than 50 days of training. In the experimental group an initial increase of working-memory related activity in the functionally defined right striatum and anatomically defined right and left putamen was followed by decreases, resulting in an inverted u-shape function that relates activity to training over time. Activity increases in the striatum developed slower in the active control group, observed at the second posttest after more than 50 days of training. In the functionally defined left striatum, initial activity increases were maintained after more extensive training and the pattern was similar for the two groups. These results shed new light on the relation between activity in the striatum (especially the putamen) and the effects of working memory training, and illustrate the importance of multiple measurements for interpreting effects of training on regional brain activity.

Place, publisher, year, edition, pages
2013. Vol. 34, no 7, 1530-1541 p.
Keyword [en]
working memory, striatum, training, fMRI
National Category
Public Health, Global Health, Social Medicine and Epidemiology
URN: urn:nbn:se:su:diva-74149DOI: 10.1002/hbm.22007ISI: 000320407500003OAI: diva2:506878
Swedish Research Council, 421-2005-2018


Sevaral other funders

Available from: 2012-03-01 Created: 2012-03-01 Last updated: 2013-07-23Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text
By organisation
Aging Research Center (ARC), (together with KI)
In the same journal
Human Brain Mapping
Public Health, Global Health, Social Medicine and Epidemiology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 51 hits
ReferencesLink to record
Permanent link

Direct link