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Separation of chiral particles in micro or nanofluidic channels
Stockholm University, Faculty of Science, Department of Physics.
2012 (English)In: Physical Review Letters, ISSN 0031-9007, Vol. 108, no 21, 214504- p.Article in journal (Refereed) Published
Abstract [en]

We propose a method to separate enantiomers in microfluidic or nanofluidic channels. It requires flow profiles that break chiral symmetry and have regions with high local shear. Such profiles can be generated in channels confined by walls with different hydrodynamic boundary conditions (e.g., slip lengths). Because of a nonlinear hydrodynamic effect, particles with different chirality migrate at different speeds and can be separated. The mechanism is demonstrated by computer simulations. We investigate the influence of thermal fluctuations (i.e., the Peclet number) and show that the effect disappears in the linear response regime. The details of the microscopic flow are important and determine which volume forces are necessary to achieve separation.

Place, publisher, year, edition, pages
2012. Vol. 108, no 21, 214504- p.
National Category
Physical Sciences
URN: urn:nbn:se:su:diva-79761DOI: 10.1103/PhysRevLett.108.214504ISI: 000304404700013OAI: diva2:551979


Available from: 2012-09-12 Created: 2012-09-11 Last updated: 2012-09-12Bibliographically approved

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