DLRS: Gene tree evolution in light of a species tree
2012 (English)In: Bioinformatics, ISSN 1367-4803, E-ISSN 1460-2059, Vol. 28, no 22, 2994-2995 p.Article in journal (Refereed) Published
PrIME-DLRS (or colloquially: 'Delirious') is a phylogenetic software tool to simultaneously infer and reconcile a gene tree given a species tree. It accounts for duplication and loss events, a relaxed molecular clock and is intended for the study of homologous gene families, for example in a comparative genomics setting involving multiple species. PrIME-DLRS uses a Bayesian MCMC framework, where the input is a known species tree with divergence times and a multiple sequence alignment, and the output is a posterior distribution over gene trees and model parameters.
Place, publisher, year, edition, pages
2012. Vol. 28, no 22, 2994-2995 p.
Bioinformatics (Computational Biology)
Research subject Numerical Analysis
IdentifiersURN: urn:nbn:se:su:diva-80681DOI: 10.1093/bioinformatics/bts548ISI: 000311303500022PubMedID: 22982573OAI: oai:DiVA.org:su-80681DiVA: diva2:556830
FunderSwedish Research Council, 2010-4634