The relative impact of the combined stresses hypoxia and ionising radiation in the marine bivalve, Mytilus edulis
(English)Manuscript (preprint) (Other academic)
A key requirement to accurate risk assessment of the impact of radioactive materials in the environment is the ability to assess the interactions and combined effects of other existing stresses or contaminants. Hypoxia is a common and growing hazard in the world’s oceans. Hypoxia is known to cause radioresistance in tumorous tissues of patients undergoing radiotherapy, however the impacts of radiation on marine organisms exposed to hypoxia is largely untested. The hypoxia tolerant bivalve – the blue mussel, Mytilus edulis - was exposed to a range of doses of gamma radiation (0.04Gy – 4Gy), following acclimatisation to either normoxia (10mgoxygen.l-1) or moderate hypoxia (3mgoxygen.l-1). Oxidative stress (lipid peroxidation) and antioxidant enzyme (catalase and superoxide dismutase) analyses were performed on tissues taken from these mussels. Very little or no effects were observed resulting from irradiation regardless of oxic treatment, however large increases in oxidative stress and antioxidant response were observed in the tissues of mussels acclimatised to hypoxia. The results suggest that the mussels are more impacted by the moderate level of hypoxia than the high doses of radiation, indicating that the endpoints or the species is not sensitive to irradiation and that historical exposure has led to adapted responses to hypoxia.
IdentifiersURN: urn:nbn:se:su:diva-83401OAI: oai:DiVA.org:su-83401DiVA: diva2:575576