Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Activation in striatum and medial temporal lobe during sequence learning in younger and older adults: relations to performance
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
2010 (English)In: NeuroImage, ISSN 1053-8119, E-ISSN 1095-9572, Vol. 50, no 3, 1303-1312 p.Article in journal (Refereed) Published
Abstract [en]

The striatum and connected cortical areas have been implicated in sequence learning (SL) tasks, in which performance increments are gradual and learning typically occurs in the absence of awareness. It has recently been shown that increasing striatal activation during SL may be accompanied by decreasing activation in the medial temporal lobe (MTL) across time, but the specific contribution of the MTL to SL remains unclear. In the current age-comparative fMRI study, we show that gradual SL in the serial reaction time task is associated with activation increases in the striatum and activation decreases in the MTL across time in younger adults. However, in older adults, SL is positively related to activation increases in both the striatum and the MTL. The results are discussed in terms of the functional role of the MTL in SL, and offer a novel explanation of the fact that SL is little affected in aging.

Place, publisher, year, edition, pages
Amsterdam: Elsevier, 2010. Vol. 50, no 3, 1303-1312 p.
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:su:diva-85337DOI: 10.1016/j.neuroimage.2010.01.015PubMedID: 20079855OAI: oai:DiVA.org:su-85337DiVA: diva2:585369
Available from: 2013-01-10 Created: 2013-01-08 Last updated: 2017-12-06Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Fischer, Håkan
By organisation
Aging Research Center (ARC), (together with KI)
In the same journal
NeuroImage
Neurosciences

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 14 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf