INTRODUCTION/OBJECTIVES: Although a substantial proportion of the population experiences dyspepsia, only a minority of them seek medical care.
AIMS & METHODS: The aim of this prospective multi-centre study was to determine the prevalence of investigated and uninvestigated dyspepsia in a representative sample of general non-selected population of the Czech Republic. A total of 1,837 subjects (aged 5-98 years) from 22 centres corresponding well to the geographical distribution entered the study. Two-step random selection was performed centrally out of 38,147 people from the registered general population. Helicobacter pylori (Hp) infection was investigated by means of 13C-UBT (INFAI, Köln, Germany). There were no preliminary exclusion criteria. Symptoms of dyspepsia, with severity measured on a scale from zero (no problems) to 10 (the worst problems), social and demographic characteristics were obtained from self-completed questionnaires from particular subjects and other health-related data were retrieved from records of general practitioners.
RESULTS: Most of the people considered themselves to be healthy (87.2%; 1602/1,837). Dyspeptic symptoms (frequently recurrent or lasting longer than 6 months) were reported by only 12.3% (226/1,837) of subjects. Those suffering from dyspepsia mostly evaluated their symptoms as acceptable (mean severity score 4.3±1.8; median 5.0). Only 48.7% (110/226) of people suffering from recurrent or long-lasting dyspepsia sought medical care and were investigated by a specialist. Dyspepsia as the only long-lasting symptom and the subjects feeling otherwise healthy was found mostly among younger subjects and/or those with higher education. These subjects might fulfil criteria for functional dyspepsia in most cases. Subjects with dyspepsia as part of a complex of previously recognised diseases are mostly older people (with structural/organic or secondary dyspepsia). The prevalence of dyspepsia (of any type) seemed to be higher among women (54.9%; 124/226 vs. 45.1%; 102/226; NS). Results of the 13C-UBT for Hp status were obtained in 99.5% (1,828/1,837) of subjects. The overall prevalence of Hp infection was 23.6% (432/1828). There was no difference in dyspeptic symptoms between Hp-positive and Hp-negative subjects.
CONCLUSION: The prevalence of dyspepsia in the Czech Republic is comparable with data from other European countries. We have found no association between Hp and the presence or absence of dyspepsia in our setting. There are clearly distinct subgroups of dyspeptic patients that should be further studied.
20th United European Gastroenterology Week, October 20-24, 2012, Amsterdam, The Netherlands
Number of poster: P0993.