The thesis objective is to use lake sediments to investigate the relationships between chironomids, as proxy for temperature, and δ¹⁸O and minerogenic in-wash, as precipitation proxies, in northern Sweden during the Late Holocene. Three lakes along a N–S transect in the Scandes were studied using biological, geochemical and physical sediment properties, together with numerical methods. Emphasis was put on changes in hydrological and erosional regimes and the configurations of lake catchments in an attempt to avoid misinterpretation of the climate signals. Mean July air temperatures were inferred from the chironomid composition in sediment records covering the last 5000 yrs in Vindelfjällen Mountains in Mid Lapland and the last 1000 yrs in Jämtland. The temperature reconstructions underwent significance tests, suggesting reliable results for the Vindelfjällen reconstruction but not the Jämtland reconstruction. Data from XRF core scanning and grain size variations, interpreted together with catchment geomorphology, suggested periods with increased fluvial erosion. A major flood event occurred at the Vindelfjällen site c. 2800 cal. yr BP. Furthermore, this record indicates stream flow and wetland surface erosion during the last 1200 yrs. Seasonal variations in the amount of precipitation, reflecting changes in atmospheric circulation during the last 1000 yrs, were reconstructed based on δ¹⁸O in diatoms from one lake in Jämtland and one in northern Lapland. Relatively higher summer precipitation was inferred between AD 1000 and 1080, AD 1300 and 1440, and during the early 19^th century as a result of a positive Arctic Oscillation mode. Changes in chironomid composition in the Jämtland lake were concurrent with shifts in δ¹⁸O_diatom suggesting indirect responses to circulation changes. Changes in precipitation are suggested to be an important factor that may cause the spatially variable results among chironomid-based July air temperature reconstructions in Scandinavia.