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Clinical implications from drug-drug and drug-disease interactions in older people
Stockholm University, Faculty of Social Sciences, Aging Research Center (ARC), (together with KI).
2013 (English)In: Clinical and experimental pharmacology & physiology, ISSN 0305-1870, E-ISSN 1440-1681, Vol. 40, no 5, 320-325 p.Article, review/survey (Refereed) Published
Abstract [en]

This clinical review summarizes the evidence in relation to clinical outcomes from drugdrug and drugdisease interactions in older people. Exposure to drugdrug interactions is associated with increased risk of hospitalization-related outcomes in older people. Drugdisease interactions have been linked with adverse drug interactions and adverse drug events in studies of older people. Although the prevalence of drugdrug and drugdisease interactions is common in older people, there are very limited empirical data on important clinical outcomes from drugdrug and drugdisease interactions. Clinical implications of interactions between drugs and geriatric syndromes such as frailty, falls, cognitive impairment, immobility and urinary incontinence should also be considered in older people.

Place, publisher, year, edition, pages
2013. Vol. 40, no 5, 320-325 p.
Keyword [en]
drug-disease interactions, drug-drug interactions, older people, clinical outcomes, prevalence
National Category
Pharmacology and Toxicology Physiology
URN: urn:nbn:se:su:diva-90350DOI: 10.1111/1440-1681.12081ISI: 000318235100002OAI: diva2:632030


Available from: 2013-06-24 Created: 2013-06-03 Last updated: 2014-01-28Bibliographically approved

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Clinical and experimental pharmacology & physiology
Pharmacology and ToxicologyPhysiology

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