Change search
ReferencesLink to record
Permanent link

Direct link
Gestational age-related changes in the peripheral blood cell composition of sub-Saharan African women
Show others and affiliations
2013 (English)In: Journal of Reproductive Immunology, ISSN 0165-0378, E-ISSN 1872-7603, Vol. 98, no 1-2, 21-28 p.Article in journal (Refereed) Published
Abstract [en]

Gestational age-related changes in the cellular composition of peripheral blood have not been described in sub-Saharan African settings. We conducted longitudinal cohort studies in Beninese and Tanzanian mothers with quantification of peripheral blood mononuclear cell-types ex vivo using flow cytometry. Between the second trimester and delivery the frequency of CD4(+) T cells declined significantly, contrasting with a non-significant increase in CD8(+) T cells, but no changes in T-regulatory, NK or NKT cell frequencies. Antigen-presenting cell profiles were also unaltered, although non-significant trends were evident. These changes resemble in some respects those reported during pregnancies in developed countries, but differ in others.

Place, publisher, year, edition, pages
2013. Vol. 98, no 1-2, 21-28 p.
Keyword [en]
Pregnancy, Peripheral blood mononuclear cells, African women, Longitudinal cohort study, Lymphocytes, Antigen-presenting cells
National Category
URN: urn:nbn:se:su:diva-92134DOI: 10.1016/j.jri.2013.03.002ISI: 000320220500003OAI: diva2:637779
EU, FP7, Seventh Framework Programme, 200889


Available from: 2013-07-22 Created: 2013-07-19 Last updated: 2013-07-22Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Troye-Blomberg, Marita
By organisation
Department of Molecular Biosciences, The Wenner-Gren Institute
In the same journal
Journal of Reproductive Immunology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 102 hits
ReferencesLink to record
Permanent link

Direct link