Change search
ReferencesLink to record
Permanent link

Direct link
A five year diagnostic follow-up of 1840 patients after a first episode non-schizophrenia and non-affective psychosis
Stockholm University, Faculty of Social Sciences, Centre for Health Equity Studies (CHESS).
Show others and affiliations
2013 (English)In: Schizophrenia Research, ISSN 0920-9964, E-ISSN 1573-2509, Vol. 150, no 1, 205-210 p.Article in journal (Refereed) Published
Abstract [en]


It is not clear which patients with a first psychotic episode will develop schizophrenia. We performed a diagnostic follow-up of patients treated for a first time non-affective, non-schizophrenia psychosis and explored potential predictors of a subsequent schizophrenia or schizoaffective diagnosis.


This register-based cohort study comprises individuals born between 1973 and 1978 in Sweden, with a first hospital-treated psychosis excluding schizophrenia, schizoaffective disorder, bipolar disorder and depressive disorder with psychotic symptoms (n = 1840). The patients were followed for five years regarding subsequent diagnoses. Psychiatric, social, family history of psychiatric illness, premorbid intellectual level, head injuries and obstetrical complications were investigated by logistic regression as predictors of schizophrenia or schizoaffective diagnosis.


During the follow-up, 18% were diagnosed with schizophrenia or schizoaffective disorder, 5% were diagnosed with bipolar disorder, whereas 29% were not re-admitted to a psychiatric clinic. Patients with a first-degree relative hospitalized for schizophrenia and/or bipolar disorder had an increased risk of subsequent diagnosis for schizophrenia or schizoaffective disorder (odds ratio 1.9 and 95% confidence interval 1.1 to 3.0)), whereas previous severe criminality was associated with a decreased risk (odds ratio 0.5, 95% confidence interval 0.3–0.8).


Diagnostic outcome was diverse after a first non-schizophrenia and non-affective psychosis. Family history of severe mental illness and no previous conviction for severe criminality were the strongest risk factors for a future schizophrenia or schizoaffective diagnosis.

Place, publisher, year, edition, pages
2013. Vol. 150, no 1, 205-210 p.
National Category
URN: urn:nbn:se:su:diva-92947DOI: 10.1016/j.schres.2013.07.011ISI: 000324294700034PubMedID: 23899998OAI: diva2:643278

AuthorCount: 5;

Funding Agency:

Marta and Nicke Nasvell Foundation 

Available from: 2013-08-26 Created: 2013-08-26 Last updated: 2013-10-21Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Hjern, Anders
By organisation
Centre for Health Equity Studies (CHESS)
In the same journal
Schizophrenia Research

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 29 hits
ReferencesLink to record
Permanent link

Direct link