Facile Structural Elucidation of Glycans Using NMR Spectroscopy Data and the Program CASPER: Application to the O-Antigen Polysaccharide of Escherichia coli O155
2013 (English)In: ChemPlusChem, ISSN 2192-6506, Vol. 78, no 11, 1327-1329 p.Article in journal (Refereed) Published
The program CASPER was successfully employed to rapidly elucidate a new O-antigen polysaccharide structure (obtained from a strain of Escherichia coli serogroup O155), using solelyunassigned NMR spectroscopy data as input information. Thus, what is considered the most tedious and time-consuming part of the structural elucidation process has been reduced from several hours (or even days) of manual interpretation to about four minutes of automated analysis.
Place, publisher, year, edition, pages
2013. Vol. 78, no 11, 1327-1329 p.
analytical methods, antigens, carbohydrates, CASPER, NMR spectroscopy
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-93838DOI: 10.1002/cplu.201300273ISI: 000326900600005OAI: oai:DiVA.org:su-93838DiVA: diva2:649199
FunderEU, FP7, Seventh Framework Programme, 215536Swedish Research CouncilKnut and Alice Wallenberg Foundation