Co-immobilization of an Enzyme and a Metal into the Compartments of Mesoporous Silica for Cooperative Tandem Catalysis: An Artificial Metalloenzyme
2013 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 52, no 52, 14006-14010 p.Article in journal (Refereed) Published
Surpassing nature: A hybrid catalyst in which Candida antarctica lipase B and a nanopalladium species are co-immobilized into the compartments of mesoporous silica is presented. The metal nanoparticles and the enzyme are in close proximity to one another in the cavities of the support. The catalyst mimics a metalloenzyme and was used for dynamic kinetic resolution of a primary amine in high yield and excellent enantioselectivity.
Place, publisher, year, edition, pages
2013. Vol. 52, no 52, 14006-14010 p.
artificial deracemase, biocatalysis, dynamic kinetic resolution, hybrid catalysts, metal catalysis
IdentifiersURN: urn:nbn:se:su:diva-96701DOI: 10.1002/anie.201306487ISI: 000328531100019OAI: oai:DiVA.org:su-96701DiVA: diva2:667174
FunderSwedish Research CouncilKnut and Alice Wallenberg Foundation
AuthorCount: 7;2013-11-252013-11-252014-02-25Bibliographically approved