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Long-term effects and secondary tumors
Linköping University, Sweden.ORCID iD: 0000-0001-8171-2541
Stockholm University, Faculty of Science, Department of Physics. Karolinska Institutet, Sweden.ORCID iD: 0000-0002-7101-240X
2014 (English)In: Comprehensive biomedical physics: Volume 9: Radiation Therapy Physics and Treatment Optimization / [ed] Anders Brahme, Amsterdam: Elsevier, 2014, 223-233 p.Chapter in book (Refereed)
Abstract [en]

The issue of secondary tumours as long-term effects of radiation therapy has gained increased importance as the life expectancy of cancer patients has increased due to improvements in detecting and treating their primary tumours. Current knowledge indicates that radiotherapy leads to a small but significant risk of inducing cancers which is often referred to as the price to pay for the effectiveness of this treatment modality. Nevertheless, the levels of incidence for the long-term effects of radiation therapy may be influenced by many factors that could be both treatment-related and patient-related and therefore proposals have been made to include risk estimations in the process of treatment optimisation. This chapter summarises the current knowledge concerning the induction of secondary cancers after radiotherapy and discusses their consequences for the therapeutic use of ionising radiation.

Place, publisher, year, edition, pages
Amsterdam: Elsevier, 2014. 223-233 p.
National Category
Cancer and Oncology
URN: urn:nbn:se:su:diva-97470DOI: 10.1016/B978-0-444-53632-7.00905-9ISBN: 978-0-444-53632-7OAI: diva2:678205
Available from: 2013-12-11 Created: 2013-12-11 Last updated: 2015-07-27Bibliographically approved

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Dasu, AlexandruToma-Dasu, Iuliana
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