Change search
ReferencesLink to record
Permanent link

Direct link
Application of an independent dose calculation software for estimating the impact of inter-fractional setup shifts in Helical Tomotherapy treatments
Stockholm University, Faculty of Science, Department of Physics. Karolinska Institute, Sweden.
Show others and affiliations
2013 (English)In: Physica medica (Testo stampato), ISSN 1120-1797, E-ISSN 1724-191X, Vol. 29, no 6, 615-623 p.Article in journal (Refereed) Published
Abstract [en]

The purpose of this study is to validate the capability of in-house independent point dose calculation software to be used as a second check for Helical Tomotherapy treatment plans. The software performed its calculations in homogenous conditions (using the Cheese phantom, which is a cylindrical phantom with radius 15 cm and length 18 cm) using a factor-based algorithm. Fifty patients, who were treated for pelvic (10), prostate (14), lung (10), head 82 neck (12) and brain (4) cancers, were used. Based on the individual patient kVCT images and the pretreatment MVCT images for each treatment fraction, the corresponding daily patient setup shifts in the IEC-X, IEC-Y, and IEC-Z directions were registered. For each patient, the registered fractional setup shifts were grouped into systematic and random shifts. The average systematic dosimetric variations showed small dose deviation for the different cancer types (1.0%-3.0%) compared to the planned dose. Of the fifty patients, only three had percent differences larger than 5%. The average random dosimetric variations showed relatively small dose deviations (0.2%-1.1%) compared to the planned dose. None of the patients had percent differences larger than 5%. By examining the individual fractions of each patient, it is observed that only in 31 out of 1358 fractions the percent differences exceeded the border of 5%. These results indicate that the overall dosimetric impact from systematic and random variations is small and that the software is a capable platform for independent point dose validation for the Helical Tomotherapy modality. (C) 2012 Associazione Italiana di Fisica Medica.

Place, publisher, year, edition, pages
2013. Vol. 29, no 6, 615-623 p.
Keyword [en]
Helical Tomotherapy, Independent point dose calculation, Patient setup, Inter-fractional shifts
National Category
Physical Sciences Radiology, Nuclear Medicine and Medical Imaging
URN: urn:nbn:se:su:diva-97664DOI: 10.1016/j.ejmp.2012.09.001ISI: 000326913700006OAI: diva2:680399


Available from: 2013-12-18 Created: 2013-12-16 Last updated: 2013-12-18Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Mavroidis, Panayiotis
By organisation
Department of Physics
In the same journal
Physica medica (Testo stampato)
Physical SciencesRadiology, Nuclear Medicine and Medical Imaging

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 14 hits
ReferencesLink to record
Permanent link

Direct link