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Brown adipose tissue as an anti-obesity tissue in humans
Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute.
2014 (English)In: Obesity Reviews, ISSN 1467-7881, E-ISSN 1467-789X, Vol. 15, no 2, 92-106 p.Article in journal (Refereed) Published
Abstract [en]

During the 11th Stock Conference held in Montreal, Quebec, Canada, world-leading experts came together to present and discuss recent developments made in the field of brown adipose tissue biology. Owing to the vast capacity of brown adipose tissue for burning food energy in the process of thermogenesis, and due to demonstrations of its presence in adult humans, there is tremendous interest in targeting brown adipose tissue as an anti-obesity tissue in humans. However, the future of such therapeutic approaches relies on our understanding of the origin, development, recruitment, activation and regulation of brown adipose tissue in humans. As reviewed here, the 11th Stock Conference was organized around these themes to discuss the recent progress made in each aspect, to identify gaps in our current understanding and to further provide a common groundwork that could support collaborative efforts aimed at a future therapy for obesity, based on brown adipose tissue thermogenesis.

Place, publisher, year, edition, pages
2014. Vol. 15, no 2, 92-106 p.
Keyword [en]
Brown adipose tissue, energy expenditure, sympathetic nervous system, uncoupling protein-1
National Category
Biological Sciences
URN: urn:nbn:se:su:diva-100856DOI: 10.1111/obr.12116ISI: 000329877900002OAI: diva2:698230


Available from: 2014-02-20 Created: 2014-02-17 Last updated: 2014-02-20Bibliographically approved

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Nedergaard, Jan
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