Catalytic Reductive Dehydration of Tertiary Amides to Enamines under Hydrosilylation Conditions
2014 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 16, no 3, 680-683 p.Article in journal (Refereed) Published
Tertiary amides are efficiently reduced to their corresponding enamines under hydrosilylation conditions, using a transition-metal-free catalytic protocol based on t-BuOK (5 mol %) and (MeO)(3)SiH or (EtO)(3)SiH as the reducing agent. The enamines were formed with high selectivity in good-to-excellent yields.
Place, publisher, year, edition, pages
2014. Vol. 16, no 3, 680-683 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-102074DOI: 10.1021/ol403302gISI: 000331163900010OAI: oai:DiVA.org:su-102074DiVA: diva2:708689
FunderSwedish Research CouncilKnut and Alice Wallenberg Foundation