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GradientOptimizer: An open-source graphical environment for calculating optimized gradients in reversed-phase liquid chromatography
Stockholm University, Faculty of Science, Department of Biochemistry and Biophysics. Stockholm University, Science for Life Laboratory (SciLifeLab).
2014 (English)In: Proteomics, ISSN 1615-9853, E-ISSN 1615-9861, Vol. 14, no 12, 1464-1466 p.Article in journal (Refereed) Published
Abstract [en]

We here present GradientOptimizer, an intuitive, lightweight graphical user interface to design nonlinear gradients for separation of peptides by reversed-phase liquid chromatography. The software allows to calculate three types of nonlinear gradients, each of them optimizing a certain retention time distribution of interest. GradientOptimizer is straightforward to use, requires minimum processing of the input files, and is supported under Windows, Linux, and OS X platforms. The software is open-source and can be downloaded under an Apache 2.0 license at

Place, publisher, year, edition, pages
2014. Vol. 14, no 12, 1464-1466 p.
Keyword [en]
Bioinformatics, Chromatography, Retention time, RPLC
National Category
Biochemistry and Molecular Biology
URN: urn:nbn:se:su:diva-106100DOI: 10.1002/pmic.201400036ISI: 000337616100003OAI: diva2:735345


Available from: 2014-07-25 Created: 2014-07-21 Last updated: 2014-07-25Bibliographically approved

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Moruz, Luminita
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Department of Biochemistry and BiophysicsScience for Life Laboratory (SciLifeLab)
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