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Selectivity in fragmentation of N-methylacetamide after resonant K-shell excitation
Stockholm University, Faculty of Science, Department of Physics.
Stockholm University, Faculty of Science, Department of Physics. Uppsala University, Sweden; Jan Kochanowski University, Poland.
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Number of Authors: 10
2014 (English)In: Physical Chemistry, Chemical Physics - PCCP, ISSN 1463-9076, E-ISSN 1463-9084, Vol. 16, no 29, 15231-15240 p.Article in journal (Refereed) Published
Abstract [en]

The fragmentation pattern of the peptide model system, N-methylacetamide, is investigated using ion time-of-flight (TOF) spectroscopy after resonant K-shell excitation. Corresponding near-edge X-ray absorption fine structure (NEXAFS) spectra recorded at high resolution at the C1s, N1s and O1s edges are presented. Analysis of the ion TOF data reveals a multitude of fragmentation channels and dissociation pathways. Comparison between the excitation of six different resonances in the vicinity of the C1s, N1s and O1s edges suggests evidence for site-selective bond breaking. In particular the breaking of the peptide bond and the N-C-alpha bond show a clear correlation with resonant excitation at the N1s edge. Also, stronger tendencies towards site-selective bond breaking are found for the generation of single ions compared with ion pairs. Analysis of angular distributions of ions from breakage of the peptide bond yields a fragmentation time of <400 fs.

Place, publisher, year, edition, pages
2014. Vol. 16, no 29, 15231-15240 p.
National Category
Physical Sciences Chemical Sciences
URN: urn:nbn:se:su:diva-106772DOI: 10.1039/c4cp01067aISI: 000339173700022OAI: diva2:738757


Available from: 2014-08-19 Created: 2014-08-19 Last updated: 2014-08-19Bibliographically approved

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Salén, PeterKaminska, Magdalenavan der Meulen, Peter
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