Acid- and Iridium-Catalyzed Tandem 1,3-Transposition/3,1-Hydrogen Shift/Chlorination of Allylic Alcohols
2015 (English)In: ACS Catalysis, ISSN 2155-5435, E-ISSN 2155-5435, Vol. 5, no 2, 708-714 p.Article in journal (Refereed) Published
A method for the selective synthesis of alpha-chlorocarbonyls from allylic alcohols is presented. The reaction occurs through an acid- and iridium-catalyzed tandem process that combines a 1,3-transposition, a 3,1-hydrogen shift, and a chlorination process, and can be applied to a wide range of alpha-aromatic and heteroaromatic secondary allylic alcohols. Saturated non-chlorinated ketones or other side-products derived from overchlorination were not detected.
Place, publisher, year, edition, pages
2015. Vol. 5, no 2, 708-714 p.
hydrogen transfer, chlorination, allylic alcohols, isomerization, iridium, 1, 3-transposition
IdentifiersURN: urn:nbn:se:su:diva-115698DOI: 10.1021/cs501618hISI: 000349275300026OAI: oai:DiVA.org:su-115698DiVA: diva2:799258
FunderKnut and Alice Wallenberg FoundationSwedish Research CouncilBerzelii Centre EXSELENT