Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Synthesis of Aryl Ethers: Metal-Free Arylation of Alcohols using Diaryliodonium Salts
Stockholm University, Faculty of Science, Department of Organic Chemistry.
2015 (English)Licentiate thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis contains two parts showing different metal-free methods to synthesize aryl ethers using hypervalent iodine reagents, more specifically diaryliodonium salts. The first part describes arylation of benzylic and allylic alcohols and phenols in water using the easily accessible base sodium hydroxide. Chemoselectivity of phenols in aqueous media is discussed and limitations of the reaction are presented.

The second part describes an arylation of aliphatic alcohols at room temperature with short reaction time and no excess of reagents are required. The scope of the methodology was investigated and showed that electron-deficient iodonium salts worked efficiently, but unfortunately electron-rich was not compatible with the reaction conditions. The methodology was applied in a formal synthesis of Butoxycaine.

Place, publisher, year, edition, pages
Stockholm: Department of Organic Chemistry, Stockholm University , 2015. , 42 p.
National Category
Organic Chemistry
Identifiers
URN: urn:nbn:se:su:diva-116183OAI: oai:DiVA.org:su-116183DiVA: diva2:802623
Presentation
2015-04-30, Magnélisalen, 10:00 (English)
Available from: 2015-04-13 Created: 2015-04-13 Last updated: 2015-04-13Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Lindstedt, Erik
By organisation
Department of Organic Chemistry
Organic Chemistry

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 174 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf