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Operational guidance for radiation emergency response organisations in Europe for using biodosimetric tools developed in EU MULTIBIODOSE project
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Number of Authors: 13
2015 (English)In: Radiation Protection Dosimetry, ISSN 0144-8420, E-ISSN 1742-3406, Vol. 164, no 1-2, 165-169 p.Article in journal (Refereed) Published
Abstract [en]

In the event of a large-scale radiological emergency, the triage of individuals according to their degree of exposure forms an important initial step of the accident management. Although clinical signs and symptoms of a serious exposure may be used for radiological triage, they are not necessarily radiation specific and can lead to a false diagnosis. Biodosimetry is a method based on the analysis of radiation-induced changes in cells of the human body or in portable electronic devices and enables the unequivocal identification of exposed people who should receive medical treatment. The MULTIBIODOSE (MBD) consortium developed and validated several biodosimetric assays and adapted and tested them as tools for biological dose assessment in a mass-casualty event. Different biodosimetric assays were validated against the 'gold standard' of biological dosimetry-the dicentric assay. The assays were harmonised in such a way that, in an emergency situation, they can be run in parallel in a network of European laboratories. The aim of this guidance is to give a concise overview of the developed biodosimetric tools as well as how and when they can be used in an emergency situation.

Place, publisher, year, edition, pages
2015. Vol. 164, no 1-2, 165-169 p.
National Category
Earth and Related Environmental Sciences Health Sciences Mechanical Engineering Clinical Medicine
URN: urn:nbn:se:su:diva-117740DOI: 10.1093/rpd/ncu294ISI: 000353546100036OAI: diva2:817517
Available from: 2015-06-05 Created: 2015-06-01 Last updated: 2015-06-05Bibliographically approved

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Wojcik, Andrzej
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Department of Molecular Biosciences, The Wenner-Gren Institute
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