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Response and recovery of Baltic Sea blue mussels from exposure to pharmaceuticals
Stockholm University, Faculty of Science, Department of Ecology, Environment and Plant Sciences.
Stockholm University, Faculty of Science, Department of Ecology, Environment and Plant Sciences.
Stockholm University, Faculty of Science, Department of Applied Environmental Science (ITM).
Stockholm University, Faculty of Science, Department of Applied Environmental Science (ITM).
Number of Authors: 4
2015 (English)In: Marine Ecology Progress Series, ISSN 0171-8630, E-ISSN 1616-1599, Vol. 526, 89-100 p.Article in journal (Refereed) Published
Abstract [en]

Physiological responses to, and recovery from, exposure to 3 concentrations of a pharmaceutical mixture (diclofenac and propranolol) were examined experimentally in Baltic Sea blue mussels Mytilus edulis trossulus collected with increasing distance to a wastewater treatment plant (WTP) outlet. Respiration, absorption efficiency and consumption were measured, and also combined into scope for growth (SFG). The response and recovery patterns varied both between exposure concentrations and sampling site within the bay. After exposure, mussels exposed to the highest concentration (2000 mu g l(-1)) in general had lower SFG, and mussels from 2 (out of 3) sites exposed to the medium concentration (200 mu g l(-1)) had higher SFG than the controls. In general, mussels from the 2 sites nearest the WTP recovered from the exposure response, while individuals collected further from the WTP outlet were more affected by the exposure and did not recover to the same extent. The response pattern of consumption was mainly affected by exposure concentration, whereas respiration was affected by all 3 factors (concentration, time of measurement, sampling site). Absorption efficiency was not affected at all. The differences in responses and recovery patterns could possibly be explained by the mussels sampled closer to the WTP having a history of higher food availability, improving their general health status, and/or a history of pre-exposure to natural disturbances, as well as to the test substances, via the WTP effluent. Pre-exposure to stressors could have both positive and negative impact on a community by increasing the resilience towards some stressors, but may also reduce the adaptability when facing other stressors.

Place, publisher, year, edition, pages
2015. Vol. 526, 89-100 p.
Keyword [en]
Mytilus edulis trossulus, Baltic Sea, Physiology, Pollutants, Disturbance recovery, Pre-exposure, Effluent gradient
National Category
Biological Sciences Earth and Related Environmental Sciences
Research subject
URN: urn:nbn:se:su:diva-117721DOI: 10.3354/meps11213ISI: 000354394900007OAI: diva2:819166
Available from: 2015-06-10 Created: 2015-06-01 Last updated: 2016-05-06Bibliographically approved
In thesis
1. Pharmaecological perspectives: Exposure studies using coastal Baltic Sea organisms
Open this publication in new window or tab >>Pharmaecological perspectives: Exposure studies using coastal Baltic Sea organisms
2014 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

This thesis investigates the effects of pharmaceutical substances on coastal Baltic Sea organisms. Despite an increasing awareness of the occurrence of pharmaceuticals in various aquatic compartments, current knowledge of their possible effects on non-target organisms is limited. Especially scarce is the knowledge concerning possible long-term effects, mixture-effects, effects on non-standard test organisms and indirect effects from interactions among organisms. Also the environmental fate, availability and distribution of pharmaceuticals between sediment, water and biota is only rarely investigated.

The aim of this thesis was therefore to investigate the biological effects of pharmaceuticals, and their distribution in organisms of a coastal Baltic Sea community. In four studies, blue mussels, amphipods and macroalgae were exposed to pharmaceuticals in laboratory experiments. The effects from exposure, as well as recovery from the same, were studied on different physiological variables. With increasing complexity of experiment designs, the tested substances were found to affect aquatic organisms from different hierarchical levels both through direct negative effects, as well as through indirect positive effects within model communities. Moreover, the studies showed that the organisms were affected by exposure to environmentally relevant concentrations, but also that exposed organisms could recover from the exposure. Effects from pharmaceutical mixtures occurred in lower concentrations than effects from single pharmaceutical substances, and high internal concentrations of two pharmaceuticals – diclofenac and propranolol – were detected in exposed organisms.

The detected effects and the uptake of pharmaceuticals in biota demonstrate a possible problem for aquatic environments, but especially for the Baltic Sea, since this is a naturally sensitive ecosystem with low species diversity, low functional redundancy and a history of heavy pollution.

Place, publisher, year, edition, pages
Stockholm: Department of Ecology, Environment and Plant Sciences, Stockholm Univeristy, 2014. 58 p.
Pharmaceuticals, Baltic Sea, Mytilus edulis trossulus, Fucus vesiculosus, Ceramium tenuicorne, Gammarus spp., Direct effects, Inter-specific interactions
National Category
Research subject
Marine Ecotoxicology
urn:nbn:se:su:diva-101160 (URN)978-91-7447-871-6 (ISBN)
Public defence
2014-04-04, Nordenskiöldsalen, Geovetenskapens hus, Svante Arrhenius väg 12, Stockholm, 13:30 (English)

At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 2: Manuscript. Paper 4: Manuscript.

Available from: 2014-03-13 Created: 2014-02-27 Last updated: 2016-05-06Bibliographically approved

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Kumblad, LindaOskarsson, HannaEriksson Wiklund, Ann-Kristin
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