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Phytochemicals and antimicrobial potentials of mahogany family
Stockholm University, Faculty of Science, Department of Molecular Biosciences, The Wenner-Gren Institute. Sri Venkateswara University, India.
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Number of Authors: 5
2015 (English)In: Revista Brasileira de Farmacognosia, ISSN 0102-695X, E-ISSN 1981-528X, Vol. 25, no 1, 61-83 p.Article, review/survey (Refereed) Published
Abstract [en]

Drug resistance to human infectious diseases caused by pathogens lead to premature deaths through out the world. Plants are sources for wide variety of drugs used for treating various diseases. Systematic screening of medicinal plants for the search of new antimicrobial drug candidates that can inhibit the growth of pathogens or kill with no toxicity to host is being continued by many laboratories. Here we review the phytochemical investigations and biological activities of Meliaceae. The mahogany (Meliaceae) is family of timber trees with rich source for limonoids. So far, amongst the different members of Meliaceae, Azadirachta indica and Melia dubia have been identified as the potential plant systems possessing a vast array of biologically active compounds which are chemically diverse and structurally complex. Despite biological activities on different taxa of Meliaceae have been carried out, the information of antibacterial and antifungal activity is a meager with exception to Azadirachta indica. Together we provide new insights of Meliaceae members demonstrating as a potential source as antimicrobial agents using in vitro studies.

Place, publisher, year, edition, pages
2015. Vol. 25, no 1, 61-83 p.
Keyword [en]
Limonoids, Flavonoids, Antibacterial, Antifungal activity
National Category
Basic Medicine
URN: urn:nbn:se:su:diva-118298DOI: 10.1016/j.bjp.2014.11.009ISI: 000354228800011OAI: diva2:821934
Available from: 2015-06-16 Created: 2015-06-15 Last updated: 2015-06-16Bibliographically approved

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Chiruvella, Kishore K.
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Department of Molecular Biosciences, The Wenner-Gren Institute
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