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Bacteria-Mediated Effects of Antibiotics on Daphnia Nutrition
Stockholm University, Faculty of Science, Department of Environmental Science and Analytical Chemistry.
Stockholm University, Faculty of Science, Department of Environmental Science and Analytical Chemistry.
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Number of Authors: 6
2015 (English)In: Environmental Science and Technology, ISSN 0013-936X, E-ISSN 1520-5851, Vol. 49, no 9, 5779-5787 p.Article in journal (Refereed) Published
Abstract [en]

In polluted environments, contaminant effects may be manifested via both direct toxicity to the host and changes in its microbiota, affecting bacteria host interactions. In this context, particularly relevant is exposure to antibiotics released into environment. We examined effects of the antibiotic trimethoprim on microbiota of Daphnia magna and concomitant changes in the host feeding. In daphnids exposed to 0.25 mg L-1 trimethoprim for 24 h, the microbiota was strongly affected, with (1) up to 21-fold decrease in 16S rRNA gene abundance and (2) a shift from balanced communities dominated by Curvibacter, Aquabacterium, and Limnohabitans in controls to significantly lower diversity under dominance of Pelomonas in the exposed animals. Moreover, decreased feeding and digestion was observed in the animals exposed to 0.25-2 mg L-1 trimethoprim for 48 h and then fed C-14-labeled algae. Whereas the proportion of intact algal cells in the guts increased with increased trimethoprim concentration, ingestion and incorporation rates as well as digestion and incorporation efficiencies decreased significantly. Thus, antibiotics may impact nontarget species via changes in their microbiota leading to compromised nutrition and, ultimately, growth. These bacteria-mediated effects in nontarget organisms may not be unique for antibiotics, but also relevant for environmental pollutants of various nature.

Place, publisher, year, edition, pages
2015. Vol. 49, no 9, 5779-5787 p.
National Category
Environmental Engineering Earth and Related Environmental Sciences
Research subject
Applied Environmental Science
URN: urn:nbn:se:su:diva-118366DOI: 10.1021/acs.est.5b00833ISI: 000354155800063OAI: diva2:822187
Available from: 2015-06-16 Created: 2015-06-15 Last updated: 2015-09-03Bibliographically approved

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Gorokhova, ElenaFuruhagen, SaraEk, KarinBreitholtz, Magnus
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