The Use of Porous Palladium(II)-polyimine in Cooperatively-catalyzed Highly Enantioselective Cascade Transformations
Number of Authors: 8
2015 (English)In: Advanced Synthesis and Catalysis, ISSN 1615-4150, E-ISSN 1615-4169, Vol. 357, no 9, 2150-2156 p.Article in journal (Refereed) Published
Porous organic polymers have prospects as functional substrates for catalysis, with quite different molecular properties from inorganic substrates. Here we disclose for the first time that porous palladium(II)-polyimines are excellent catalysts for cooperatively catalyzed and enantioselective cascade reactions. In synergy with a chiral amine co-catalyst, polysubstituted cyclopentenes and spirocyclic oxindoles, including the all-carbon quaternary stereocenter, were synthesized in high yields. High diastereo- and enantioselectivities were achieved for these dynamic kinetic asymmetric transformations (DYKAT) of enals with propargylic nucleophiles.
Place, publisher, year, edition, pages
2015. Vol. 357, no 9, 2150-2156 p.
cascade reaction, cooperative catalysis, enantioselective synthesis, heterogeneous catalysis, palladium, porous organic polymers
Research subject Materials Chemistry
IdentifiersURN: urn:nbn:se:su:diva-118958DOI: 10.1002/adsc.201500100ISI: 000356373200023OAI: oai:DiVA.org:su-118958DiVA: diva2:842735