Artificial Metalloenzymes in Asymmetric Catalysis: Key Developments and Future Directions
2015 (English)In: Advanced Synthesis and Catalysis, ISSN 1615-4150, E-ISSN 1615-4169, Vol. 357, no 8, 1567-1586 p.Article in journal (Refereed) Published
Artificial metalloenzymes combine the excellent selective recognition/binding properties of enzymes with transition metal catalysts, and therefore many asymmetric transformations can benefit from these entities. The search for new successful strategies in the construction of metal-enzyme hybrid catalysts has therefore become a very active area of research. This review discusses all the developed strategies and the latest advances in the synthesis and application in asymmetric catalysis of artificial metalloenzymes with future directions for their design, synthesis and application (Sections 2-4). Finally, advice is presented (to the non-specialist) on how to prepare and use artificial metalloenzymes (Section 5).
Place, publisher, year, edition, pages
WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim , 2015. Vol. 357, no 8, 1567-1586 p.
artificial metalloenzymes, asymmetric catalysis, hybrid catalysts
IdentifiersURN: urn:nbn:se:su:diva-118535DOI: 10.1002/adsc.201500290ISI: 000355235700002OAI: oai:DiVA.org:su-118535DiVA: diva2:846596
FunderSwedish Research CouncilBerzelii Centre EXSELENTKnut and Alice Wallenberg Foundation