C-N Coupling of Amides with Alcohols Catalyzed by N-Heterocyclic Carbene-Phosphine Iridium Complexes
2015 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 80, no 22, 11529-11537 p.Article in journal (Refereed) Published
N-heterocyclic carbene-phosphine iridium complexes (NHC-Ir) were developed/found to be a highly reactive catalyst for N-monoalkylation of amides with alcohols via hydrogen transfer. The reaction produced the desired product in high isolated yields using a wide range of substrates with low catalyst loading and short reaction times.
Place, publisher, year, edition, pages
2015. Vol. 80, no 22, 11529-11537 p.
Research subject Organic Chemistry
IdentifiersURN: urn:nbn:se:su:diva-119680DOI: 10.1021/acs.joc.5b01324ISI: 000365462600033OAI: oai:DiVA.org:su-119680DiVA: diva2:847684