Change search
ReferencesLink to record
Permanent link

Direct link
Prenatal acquired cytomegalovirus infection should be considered in children with autism
Stockholm University, Faculty of Social Sciences, Department of Psychology. University of Gothenburg, Sweden.
Show others and affiliations
Number of Authors: 7
2015 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 104, no 8, 792-795 p.Article in journal (Refereed) Published
Abstract [en]

Aim: The aim of the study was to evaluate the prevalence of congenital cytomegalovirus infection (CMV) in a representative sample of children with autism spectrum disorder. Methods: In a representative group of 115 preschool children with autism spectrum disorder, of whom 33 also had intellectual disability, the dried blood spots from the newborn metabolic screening were analysed for CMV DNA using TaqMan polymerase chain reaction. Results: One of the 33 children with autism spectrum disorder and intellectual disability - 3% of that group - had congenital CMV infection. The corresponding prevalence in newborn infants in Sweden is 0.2%. None of the 82 children without intellectual disability had congenital CMV. Conclusion: The finding lends some further support for congenital CMV being one of the many aetiologies underlying autism spectrum disorder with intellectual disability. The rate of 3% of congenital CMV in children with autism spectrum disorder with intellectual disability has implications for the medical work-up. The finding of congenital CMV also indicates the need for repeated hearing assessments in the child. There is a need for similar studies with much larger samples.

Place, publisher, year, edition, pages
2015. Vol. 104, no 8, 792-795 p.
Keyword [en]
Autism, Congenital cytomegalovirus infection, Dried blood spots, Intellectual disability
National Category
URN: urn:nbn:se:su:diva-119535DOI: 10.1111/apa.13032ISI: 000357991200017OAI: diva2:847827
Available from: 2015-08-21 Created: 2015-08-17 Last updated: 2015-08-21Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Westerlund, Joakim
By organisation
Department of Psychology
In the same journal
Acta Paediatrica

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 33 hits
ReferencesLink to record
Permanent link

Direct link